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Canelim Capsule Pharmacodynamics Experimental Information
Canelim Capsule pharmacodynamics research includes 1. Anti-cancer function; 2. Adjustment function; 3. Detoxication function; 4. Improvement of blood circulation and decongestion function; 5. Antiphlogistic and painkilling function.
In the anti-tumor researches: given a dose of 0.1-0.4g/kg of Canelim Capsule into stomach can suppress the growth of tumor in hydroperitoneum cancer and H22 tumor-bearing mice and prolong the lifespan; suppress the growth and infiltration of the solid carcinoma in S180 and H22 tumor-bearing mice, and coordinate with cyclophosphamide in resistance of tumor; suppress the growth of lung metastasis. The report explains that Canelim Capsule has the function of anti-tumor.
In the adjustment and detoxication researches: in the above given dosage of Canelim Capsule can obviously improve the resisting ability to high temperature, low temperature and anoxia; enhance the level of cellular & humoral immunity and increase the activity of dead factors of tumor. The report explains that Canelim Capsule has the function of adjustment of immunity. Canelim Capsule with the above given dosage can resist the numbers of leukocyte and myelocyte dropping after applying cyclophosphamide and radiotherapy. The report explains Canelim Capsule has the function of protecting and healing from the side-effects of chemotherapy and radiotherapy.
In the improvement of blood circulation and decongestion researches: in the above given dosage of Canelim Capsule can obviously reduce the high viscosity of blood and plasma, and improve the mesentery microcirculation of the tumor-bearing rat. The report explains that Canelim Capsule has the function of improvement of blood circulation and decongestion, and it is probably the anti-tumor function in Chinese medicine fundament.
In the antiphlogistic and painkilling experiments: in the above given dosage of Canelim Capsule can reduce the pain reaction caused by heat and chemical stimulations; reduce the swelling of auricle of tumor-bearing mice caused by xylol; reduce swelling of tarsometatarsus of tumor-bearing rat caused by ovalbumin. The experimental report explains Canelim Capsule has the function of antiphlogistic and painkilling.
The research reports state that Canelim Capsule has the functions of rectification and detoxication to anti-tumor and supplementary of anti-cancer, its anti-stimulation, painkilling and antiphlogistic improve patient's symptoms and quality of life. Improvement of blood circulation and decongestion functions and enhancement of immunity are probably the fundament of pharmacodynamics of anti-tumor functions.
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Pharmacodynamics Experimental Information
